Which removes magnesium from the body very much. For what reasons can an overdose occur?


Give me magnesium and I'll help you. So I would paraphrase Archimedes’ phrase “about the fulcrum.” I use magnesium in programs to restore hormonal balance, reduce adrenal fatigue and anxiety, and lower TSH levels - without synthetic hormones, for premenstrual syndrome.

The synthesis of FSH - follicle-stimulating hormone, LH - luteinizing hormone, TSH - thyroid-stimulating hormone of the thyroid gland occurs with the participation of magnesium, these hormones regulate follicle production and ovulation, and the functioning of the thyroid gland. Magnesium is needed not from time to time, but daily. This “revives” our nervous system. No magnesium - no energy!

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Symptoms of magnesium deficiency can be divided into 4 stages (“The magnesium miracle”, Dr. Caroline Dean)

Stage 1:

lack of energy, constipation, severe pain during menstruation, tics, headache, frequent hiccups, irritability, loss of appetite, cravings for caffeine, sweets, light carbohydrates, mood swings, weakness, during pregnancy, nervousness, muscle cramps , nausea.

Stage 2:

panic attacks, arthritis, asthma, attention deficit hyperactivity disorder, back pain, cystitis, ear infections, gluten sensitivity, insomnia, migraines, when pregnant with twins (or more), obesity, PMS, difficulty concentrating, sinusitis, resistance to insulin, reflux esophagitis - acid reflux, when the contents of the stomach reflux into the esophagus, which is accompanied by heartburn.

Stage 3:

celiac disease, cerebral palsy, depression, kidney disease, diabetes, epilepsy, cardiac arrhythmia, hormonal imbalance - decreased sexual desire, lack of ovulation, liver disease, miscarriage, osteoporosis, severe obesity.

Stage 4:

alcoholism, Alzheimer's disease, cancer (breast, rectal, prostate), late stage obesity, Parkinson's, sudden infant death syndrome, heart attack.

Drinking coffee removes magnesium.

Prescribing medications with magnesium

To cover the actual deficiency of the substance, doctors prescribe Magnesium B6 and Magnelis for irritability, muscle pain, cramps, fatigue and poor sleep.

Renal failure is the main contraindication for use. The substance does not have a toxic effect on the body if the kidneys are functioning normally. If their function malfunctions, the magnesium level in the blood increases, and signs of poisoning appear: nausea and vomiting, drop in blood pressure, lethargy, slow heartbeat, and breathing problems. With significant intoxication of the human body, coma and paralysis occur.

You need to take magnesium supplements strictly according to the indications:

  • mitral valve prolapse;
  • arterial hypertension;
  • diabetes mellitus against the background of obesity and atrosclerosis;
  • pregnancy;
  • muscle cramps in athletes;
  • stress, psycho-emotional disorders, depression.

An overdose of magnesium is possible with arbitrary long-term consumption of drugs against the background of a sufficient amount of it in the diet.

How do you know if your child needs additional sources of magnesium?

Symptoms of stress

the child has quite a variety, but they can be combined into groups, distributed by age:

  • Up to two years

The baby refuses to eat, becomes irritable, and his sleep is suddenly and unexpectedly disturbed (for example, he refuses naps or wakes up too early).

  • From two to five years

The child may again return to the pacifier, begin to urinate in his pants or in the bed. He develops excessive fears, aggressive behavior, uncontrollable outbursts of bad mood, tears as a reaction to everything new, and hyperactivity.

You can read more about hyperactivity in children on our website in the articles:

Hyperactivity - symptoms and causes. Character trait or disease?

Hyperactive child: what to do

  • From five to ten years and older


The child often complains of causeless pain and discomfort in the abdomen (sometimes vomiting), and refuses to attend school and contact with peers.

He develops inexplicable anxiety or fear, nervous tics (twitching of the eyelid, neck muscles) and stereotypical movements (turning the head, movements in the arms or legs, flexion and extension of fingers, and so on), repeated at certain intervals or occurring at night.

The baby often has low self-esteem, disturbed sleep and appetite, and decreased memory. At this age, the child usually comes to understand that all children are different. As a result, competition appears, which can adversely affect the child’s nervous system.

Causes of excess magnesium

The most common causes of excess magnesium in the body:

  1. Hard drinking water. With normal concentrations of calcium and magnesium ions in water, the heart muscle relaxes, but hard water often has a lack of ions and an excess of salts, which disrupts the functioning of the heart and causes persistent chronic arrhythmia.
  2. Acute or chronic renal failure with reduced urine output. Typically, excess amounts are immediately excreted by the kidneys, as the body strictly controls the level of the mineral in the blood.

An excess of magnesium also appears against the background of:

  • exceeding the dose of a microelement during treatment;
  • overdose of magnesium sulfate in the treatment of eclampsia in pregnant women;
  • the use of certain medications (laxatives and antacids in older people).

The consequence of long-term use of drugs without medical indications is chronic intoxication.

Main risks of magnesium intoxication

Hypermagnesemia is most often observed in people with kidney failure who start taking laxatives and antacids. Therefore, people with kidney disease need to consult a doctor about how to take medications correctly. Magnesium antacids should not be used if you have pathologies of the adrenal glands or dehydration.

Also, the risks of magnesium overdose increase with heart disease, metabolic disorders and gastrointestinal disorders, as well as with the following conditions:

  • lack of thyroid hormones;
  • disturbance of carbohydrate metabolism in diabetes mellitus;
  • decreased calcium levels in the blood;
  • slowing of heart rate and cardiac conduction;
  • urolithiasis disease.

Magnesium salt, even in large doses, does not provoke poisoning. Intravenous administration of magnesium sulfate causes intoxication, which manifests itself as weakness and drowsiness. Increasing the concentration of the mineral to 2.5-5.5 mmol/l worsens heart function.

Magnesium poisoning occurs at levels above 5 mmol/l and requires urgent action. In large doses, when blood concentrations reach 15-18%, a state of anesthesia occurs.

How to detect poisoning?

It is not difficult to recognize excess magnesium in the body by symptoms:

  • nausea and vomiting;
  • lethargy;
  • muscle weakness;
  • irregular heartbeat;
  • low blood pressure;
  • breathing problems;
  • reducing urine output.

Magnesium poisoning is fraught with depression of heart function, breathing problems (since the main respiratory muscle, the diaphragm, suffers), weakness and even paralysis.

An excess of the substance develops against the background of dyslexia (impaired ability to recognize words when reading), arthritis, psoriasis, nephrocalcinosis and hyperfunction of the thyroid gland.

Chronic excess of the substance is possible with uncontrolled use of drugs for the treatment of heart disease with impaired kidney function. Apathy and drowsiness appear, the person’s condition worsens, diseases of the digestive system worsen, diarrhea begins, and performance decreases.

Magnesium overdose

Do not confuse signs of overdose and magnesium poisoning. Even people with normal kidney function may experience abdominal pain, constipation, bloating, nausea and vomiting after taking Magnelis. Stopping the medication is sufficient to reduce symptoms.

When taking Magnelis for the first time, you should monitor reactions from the immune system. An allergy to magnesium is expressed by a rash, swelling and redness. Like any drug, mineral-vitamin complexes (such as Magvit or Magne B6) should be prescribed by a doctor after a blood test to determine the need for substances. Poisoning develops only with chronic overdose, for example, with antacids.

Treatment methods

Excess magnesium in the body, the symptoms of which in women and men can be absolutely identical, should be treated as an independent disease. This is necessary to prevent the development of complications in the form of a number of diseases. If they are detected, it is not advisable to treat individual cases of the disease if the magnesium level does not decrease.

There are 4 types of drugs that can be prescribed to eliminate excess substances:

Medicines Reception
I generationInorganic compounds - calcium oxide, magnesium sulfate in the form of salts should be taken on an outpatient basis during the course.

II generationOrganic protein compounds - lactate, citrate, pidolate and aspirginate can be taken after eliminating the symptoms of diseases that accompany excess magnesium.
III generationBiological ligands of exogenous origin are able to neutralize natural and plant components of magnesium, leaving only the necessary magnesium cells in the body.
IV generationAnalogues of endogenous ligands, which are prescribed for the recombination of magnesium forms. They contain neuropeptides, amino acids and enzymes that promote the breakdown of substance cells.

The first group of drugs affects metabolism. Side effects include vomiting and a metallic taste in the mouth. The second group has antacid properties, therefore it is recommended for correcting excess and deficiency of magnesium.

Another, 3rd group of substances helps normalize magnesium homeostasis. The latter absorbs citrate and asparginate into the gastrointestinal tract, removing 43% of all magnesium salts in 1-2 days.

Medications

Excess magnesium in the body can be recognized by test results. To take a blood test, women should not eat anything in the morning. Men can donate blood on an empty stomach at 1 p.m.

Then, based on observation of the symptoms and dynamics of the disease, additional examinations and a course of treatment may be prescribed:

  • Replacement therapy – drugs are used to provide nutritional support to the functioning of the gastrointestinal tract. During support, magnesium lactate can be administered intravenously, which helps identify the area of ​​cell damage. Cost 1 pack. Amounts to 482 rubles. For a full course, 2 packs are enough.
  • Mineral citrates can be purchased for 487-811 rubles. per pack For a course of treatment of 2 weeks, 6 dosages are required for 7 days. The drug is intended for intravenous use. It cannot be used without a prescription from a doctor who determines the dosage, as side effects include dyspeptic complications (abdominal cramps, pain, cramps and vomiting).
  • Organic salts are best absorbed when the kidneys are functioning normally. The cost of the drug is 3700-7800 per course of treatment. Injections must be carried out in a hospital setting in the form of droppers.

Traditional methods can be used as an alternative treatment.

Traditional methods

Proven folk methods for treating excess magnesium include replacement therapies, which are designed to indirectly affect the removal of minerals from the body:

  • It is necessary to completely avoid taking dietary supplements and vitamins containing magnesium.
  • It is necessary to eat foods high in magnesium along with vitamins - chocolate, nuts, almonds, soy, buckwheat.
  • Without magnesium, calcium cannot be absorbed. If there is an excess of the first, you need to increase the dosage of the second. Thus, by increasing metabolism at the cellular level, together with calcium and potassium (part of calcium complexes), the body will more quickly cleanse itself of excess substances.


    If you have too much magnesium in your body, you need to consume more calcium.

  • It is necessary to exclude fatty foods, which interfere with absorption and metabolism. The more organic substances in the blood and plasma that can remove magnesium, the better the body copes with its loss (until the norm is reached).
  • It is necessary to exclude drugs and products containing phosphorus. Fish, as a source of amino acids, can cause magnesium retention in the blood. And with a lack of calcium, the substance will accumulate in the plasma, causing complications.

Also, due to the presence of excess magnesium, diseases may develop that require additional treatment.

Other methods

Among the effective methods of treating excess magnesium is the method of replacement therapy. It is based on taking individual subgroups of vitamin B (B6 or B1). Galenic forms of the substance help other components to be absorbed into the blood faster, neutralizing the effect of magnesium. They can be purchased in the form of 0.5 g tablets containing up to 27 mg of vitamin.

Effervescent tablets contain 0.15 g of active substances, among which there are 24.4 mg of vitamins for removing magnesium from the body.

Tablets of 0.5 g with a share of vitamins up to 32.7 mg help restore a number of kidney functions and improve metabolism. In the same form, tablets containing 49.7-49.8 mg of calcium and potassium can eliminate the side effects of an overdose of the active component.

Their cost ranges from 900 to 5700 rubles. for a course of treatment. The drug can be prescribed by an endocrinologist or gynecologist, who builds a course of treatment for the woman.

How to normalize microelement levels

Before reducing the level of magnesium in the blood, you need to make sure that there is an excess. A consultation with a doctor is required who will prescribe medications and procedures to solve the problem. The indication is a blood test.

If the concentration is above 5 mmol/l and there are clear signs of overdose, 10-30 ml of a 10% calcium gluconate solution is administered intravenously. If the excess levels are insignificant, the doctor prescribes diuretics and prescribes a plentiful drinking regime. The results of treatment are monitored so as not to provoke a decrease in the indicator and calcium excretion.

In case of kidney failure, dialysis is practiced, during which the blood is purified and returned to the human body. In case of normal kidney function, but significant intoxication, solutions of sodium chloride and furosemide are administered in the required dosages with constant monitoring of cardiac function. An overdose of Magne B6 is corrected in a hospital.

a) Clinical picture of hypermagnesemia

:

Excess magnesium

. Hypermagnesemia can be caused by excessive oral intake, impaired excretion or parenteral administration of magnesium.

Excessive oral magnesium intake

. Oral overdose of magnesium in healthy kidneys and intestines is not common. It has been observed in neonates receiving Mylanta (56 mg elemental Mg in 4 ml) or Milk of Magnesia (8 teaspoons per day, i.e. 381.6 mg/kg per day). Symptoms of hypermagnesemia sometimes develop in patients who frequently take magnesium-containing laxatives due to drug overdose.

Excess orally administered magnesium can induce diarrhea with increased levels of this element in the feces. In cases of megacolon and intestinal obstruction, rectal administration of magnesium drugs has resulted in lethal hypermagnesemia.

Impaired excretion

. Hypermagnesemia has been observed in patients with chronic renal failure receiving magnesium-containing antacids, enemas, or infusions. Excess magnesium in the dialysate can also lead to symptomatic hypermagnesemia. In acute renal failure, serum magnesium levels were 2.6-3.8 mEq/L (1.3-1.9 mmol/L). Azotemia, acidosis, acute skeletal muscle necrosis, and continued oral magnesium intake contribute to hypermagnesemia.

Parenteral administration

. Symptoms of magnesium excess may occur with parenteral magnesium therapy. Administration of 250 ml of liquid containing 20 g of magnesium sulfate to one adult patient over 15 minutes led to respiratory arrest, hypotension, bradycardia, widening of the QRS complex and QT interval. Errors by medical personnel during intravenous infusion (for example, a bottle with 50 ml of 50% magnesium sulfate instead of 2 ml of this solution) can quickly induce symptoms typical of hypermagnesemia.

b) Clinical manifestations of hypermagnesemia

:

Biochemical indicators

. Symptomatic hypermagnesemia usually occurs when plasma magnesium concentrations exceed 4 mEq/L (2 mmol/L). Its parenteral administration reduces plasma calcium levels in normal and hypoparathyroid patients. Anion deficiency may not change, but osmolality may increase.

Neuromuscular structures

. Excess magnesium slows down the conduction of impulses through neuromuscular synapses. When its blood level is 4 mEq/L (2 mmol/L), a weakening or disappearance of deep tendon reflexes is observed. At 4-7 meq/l (2-3.5 mmol/l) drowsiness is noted, and at 10 meq/l (5 mmol/l) and above - flaccid paralysis of voluntary muscles. This can lead to respiratory dysfunction and apnea, which is counteracted by calcium. In the absence of deep tendon reflexes, careful monitoring of breathing is necessary.

The cardiovascular system

. At plasma magnesium levels of 4-5 meq/l (2-2.5 mmol/l), bradycardia and hypotension are possible due to its direct vasodilatory and ganglion-blocking effects at the level of peripheral arteries and arterioles. At plasma concentrations of 5-10 meq/l (2.5-5 mmol/l), an expansion of the PR and QRSw QT intervals on the ECG is observed. Complete heart block and cardiac arrest due to asystole are possible at levels of 15 mEq/L (7.5 mmol/L) and above.

With an overdose of magnesium, circulatory and respiratory arrest with coma, non-reactive pupils, flaccid limbs, loss of deep tendon reflexes and lack of response to painful stimuli are sometimes observed in the early stages.

In normal individuals, 4 g of magnesium sulfate dissolved in 20 ml of 5% glucose solution, when administered intravenously, appears to increase cardiac output and heart rate, reducing systolic blood pressure and systemic vascular resistance. This is accompanied by dilation of the coronary arterioles. Parenteral administration of magnesium sulfate appears to slow conduction in the sinus and atrioventricular nodes; it also increases the refractory period of the atrioventricular node in normal individuals and may be useful in the treatment of paroxysmal atrial fibrillation, quickly producing the desired response.

To stop torsades de pointes, magnesium sulfate (2 g over 1-2 minutes) was administered intravenously once or repeatedly, followed by continuous infusion at a rate of 3-20 mg Mg/min. For preeclampsia, this drug was used as an anticonvulsant: 4.0 g intravenously (saturating dose), and then 1.0-2.0 g/hour.

c) Treatment of hypermagnesemia

: 1. Stop the administration of magnesium. 2. If magnesium is in the intestines, remove it with an enema. 3. Activated carbon does not adsorb magnesium salts. 4. Monitor serum electrolytes, calcium, phosphorus, renal function, fluid intake, urine output and electrocardiogram. 5. Readiness for venous catheterization, oxygen therapy and cardiac monitoring. 6. If the patient is symptomatic (hypotension, central nervous system depression), ECG changes are present, and the serum magnesium level is above 2.9 mg/100 ml (2.3 mEq/L, or 1.1 mmol/L), treatment should be started. . 7. Intravenous 10% calcium gluconate: 10-20 ml for adults, 100 mg/kg for children up to a maximum of 1 g (slowly, over 5-10 minutes, with electrocardiographic monitoring). This may relieve hypotension and paralysis. In severe hypermagnesemia, calcium is indicated even if total serum levels are normal. 8. If renal function is normal, furosemide (40 mg adults, 1 mg/kg children) can be administered intravenously as an alternative, replacing urine volume with 0.89-0.90% saline. Diuresis forced with mannitol (rapid intravenous infusion of 25 g) was also useful. 9. Dialysis may be effective, and one newborn with severe magnesium toxicity received an exchange transfusion. 10. Aminoglycosides are contraindicated because they may potentiate magnesium-induced neuromuscular blockade. 11. Cardiac pacing can be useful.

Magnesium is very important for the normal functioning of the entire body. Thanks to its properties, substances are produced and protein is formed. If you drink alcohol or drink coffee every day, the amount of magnesium will decrease sharply.

On your own, you can only guess whether you have it; only a doctor can accurately diagnose it. To detect an excess of magnesium in the body, you will need to donate blood to detect this enzyme.

What is magnesium and why does the body need it?

The chemical element Mg is essentially a metal. In tissues it is contained in the form of salts and in interaction with oxygen. People get this enzyme from the foods they eat. But often it is not enough for the normal functioning of the body. In this case, the doctor will definitely prescribe medications containing Mg.

They must be taken if:

Factors of excess magnesium in the body were discovered, and its symptoms are as follows: drowsiness, convulsions, severe headache, arthritis, constipation, cardiac arrhythmia; pregnancy is not progressing well, which can lead to premature birth; feel stressed; a concussion occurred; heart diseases.

Who should not take the drugs:

hypersensitive people; patients with kidney disease; before childbirth.

Mg is widely used in pharmaceuticals. Many drugs are made on its basis. But how much magnesium should pregnant women or ordinary people take per day? This is what we have to deal with.

Daily Mg requirement

Magnesium is very important for our health. It will be constantly necessary to monitor the normal levels of this enzyme in the body. It must be supplied in a certain amount per day. Adults are advised to take 400-500 grams of Mg per day, and children - half as much for.

Indicators can increase sharply if a person is exposed to physical activity or stress, or abuses alcohol. During pregnancy, the daily dose should be many times higher.

Magnesium is able to interact with vitamins and minerals. But here it is worth choosing. Some substances help the enzyme to be absorbed, while others block its implementation. But before taking it, take into account all the features so as not to become allergic to magnesium B6. When is there not enough magnesium in the body?

An overdose of magnesium is a serious thing. But its excess also negatively affects the body. It is important to take timely measures to get rid of side effects. A person gets the necessary vitamins by consuming certain foods.

But sometimes the body doesn’t have enough of all this. To maintain your normal condition, you need to include in your menu various cereals, legumes, nuts, dairy products, as well as fruits, liver, meat products, eggs and chocolate.

Mg deficiency is determined by the following symptoms:

Fast fatiguability; insomnia; frequent body cramps; the “eye” twitches; the heart beats strongly; dizzy; numbness of arms and legs.

By taking a complex of vitamins and minerals, you will replenish your daily dose of magnesium. Large amounts of the drug will cause magnesium poisoning.

Magnesium overdose

Excess magnesium in the body has a bad effect on its well-being. The fault is with the disrupted metabolism of the incoming enzyme. Allergic indicators are extremely rare. In case of overdose, internal organs are affected, especially the kidneys. It is with these organs that malfunctions begin.

In this case, the patient experiences kidney failure and dehydration. Rarely, but still, dyslexia (inability to read) occurs. The activity of the thyroid gland also increases. An excess of magnesium provokes the development of arthritis and psoriasis. Stones form in the kidneys. A person may experience some muscle problems.

Complete atrophy occurs. The person feels tired. Thoughts develop slowly and decrease. We can conclude that with an excess of magnesium, all systems in the body begin to slow down.

If the excess enzyme level is not reduced, the symptoms will become more active. Some people are allergic to magnesium. You should immediately consult a doctor for further action.

How to help the patient?

Unfortunately, the consequences of excess magnesium are dangerous for the human body. The victim must be given first aid. The first step is to rinse the stomach. There are substances that destroy magnesium - calcium and gluconate. These two enzymes can be administered intravenously.

A doctor must be present during such manipulations. Perhaps the patient will be sent to the hospital, where they will undergo a thorough examination. An excess of the drug can be removed through the genitourinary system. To do this you will have to drink a lot of liquid.

If this fails to remove the substance, then special drugs will be used. When taking vitamins, strictly follow the instructions. Typically, an overdose of the drug is extremely rare; there are cases where patients were allergic to magnesium. But this does not apply to everyone, because we are all different and our bodies are individual. Failure to notify your doctor of an overdose can result in serious consequences.

If there is a lack of magnesium in the body, the doctor prescribes patients to take certain medications based on this enzyme.

1. We present to your attention the drug Magne B6. This is the most popular remedy that replenishes Mg in the body. The active ingredients of this drug are magnesium lactate and pyridoxine hydrochloride. These two components combine well with each other and are absorbed in the body. Magne B6 can be bought at any pharmacy. The product is available in the form of oval tablets and ampoules. Tablets should not be taken by children under 7 years of age. But as for ampoules, they can be prescribed to children from 1 year of age. This drug should not be taken together with calcium, as it neutralizes magnesium.

2. There is another very popular remedy, Cardiomagnyl. The main components of the drug are acetylsalicylic acid and magnesium hydroxide. The drug is released in the form of tablets. Admission is carried out for preventive purposes against heart diseases. This medicine should not be taken by pregnant women in the first 6 months of gestation, during breastfeeding and by persons under 18 years of age. Cardiomagnyl is also not recommended for patients with stomach ulcers and asthma. You cannot combine taking the drug with drinking alcohol.

3. Next is the drug Magnerot. The main component of this drug is magnesium orotate. The drug is available in the form of white tablets. The doctor prescribes Magnerot as a prophylaxis against heart disease, spasms and muscle pain. Overdose of the drug is excluded. You should not take pills if you have kidney problems or hypersensitive people. Persons under 18 years of age are strictly prohibited from taking this drug. Magnerot interacts poorly with oral contraceptives and diuretics.

4. Magnesium sulfate contains the component we need. The product is available in ampoules and powder form. Magnesium sulfate is an antispasmodic. The drug is able to normalize blood pressure, therefore it is prescribed to hypertensive patients. If the solution is administered intravenously, it must be done very slowly. The person may find it difficult to breathe. In a critical situation, you will need to inject calcium. It neutralizes magnesium in the body. How does Mg affect the body?

If there is a lack of magnesium in the body, the central nervous system is the first to suffer. This occurs due to electrolyte imbalance and increased potassium ions. You will see immediately if there is an overdose of magnesium. There is lethargy, loss of consciousness and shortness of breath. It is very serious. If you do not pay attention to this, in severe cases paralysis and coma occurs.

Excess Mg is capable of releasing neurotransmitters. This effect completely destroys the neuromuscular transmission of nerve impulses. With serious deviations, a decrease in muscle tone is observed. There is diarrhea, weakness of the whole body and heart failure.

Magnesium is of great importance for the body. Magnesium deficiency usually occurs in people who follow a weight loss diet for a long time. In addition, stress, poor diet, and drinking large amounts of coffee and tea lead to magnesium being washed out of the body. However, an overdose of magnesium

may be no less dangerous to health.

Is there an allergy to magnesium?

Yes, it happens, however, according to medical scientists, this is observed quite rarely and is almost impossible. Because:

  • You cannot cause an allergy to magnesium with food products, because you need to eat many kilograms of the same halva, greens, and bran at a time.
  • In any more or less normally functioning body, excess magnesium, like other elements, is excreted by the kidneys.

The only thing that can provoke an allergic reaction is the use of magnesium-containing drugs. And here it is not necessary to accuse the victim of initiative. It’s just that the concentration of Mg in tablets and injections is very high, so the body of some may incorrectly perceive such a powerful “infusion”, causing an allergic reaction.

Sometimes a person is addicted to dietary supplements and at the same time takes Mg, which may be incompatible with them. But here we return to the beginning of the article, which talked about overdose due to uncontrolled use of the drug. An allergic reaction also occurs when you take long breaks from taking magnesium, and then take it in too large dosages.

Well, the last option is obvious allergies. Everything is clear here: if your body rejects cocoa, nuts, sesame seeds, chocolate, you cannot take Mg without serious tests and a doctor’s recommendation.

Causes of excess magnesium

Excess vitamin is sometimes much worse than hypovitaminosis. Excess magnesium in the body is an extremely rare condition, but nevertheless possible. Causes of excess magnesium

in the body, in most cases, are associated with the thyroid gland and adrenal glands.
The retention of magnesium in the body
is also facilitated by the use of psychotropic drugs (necessary for the treatment of mental illness).

Excess magnesium also often accompanies cancer. As a result of cancerous changes in the body, magnesium metabolism changes. If the test reveals an increased level of magnesium in the blood

, it is likely that you are developing cancer.

Too much magnesium in the body can occur in children who eat modified milk or drink mineral water. You should pay attention to the content of magnesium ions in the water given to the child. Infants' kidneys are not as efficient as those of adults, so excess magnesium, instead of being excreted in urine, accumulates in the body.

Excess magnesium occurs

also due to the very active use of this element. Therefore, when taking vitamin and mineral preparations, you should carefully calculate the dose.

Signs of magnesium poisoning

Chronic magnesium overdose is more difficult to identify, since its symptoms at the initial stage are weak and can be easily confused with symptoms of other diseases. It is easier to ascertain with extreme accuracy using a blood test.

Therefore, here we will talk about an acute overdose of Mg, resulting from improper use of magnesium-containing medications or due to the fact that the body is not able to remove it due to illness or other weaknesses. It is observed:

  • gastrointestinal dysfunction, diarrhea,
  • nausea, vomiting,
  • feeling of chest tightness, respiratory depression,
  • severe decrease in blood pressure,
  • suppression or even absence of some natural reflexes, for example, the patella,
  • partial loss of muscle control,
  • arrhythmia, a feeling that the heart is pounding.

Why does this happen? This is due to how magnesium affects the human body. Since Mg is a powerful depressant, in case of overdose it has too strong an effect on the nervous system. The latter, to one degree or another, ceases to control the muscles. Based on this, arrhythmia occurs, reflexes disappear and breathing is impaired. Let's look at how an overdose of magnesium disrupts the functioning of individual body systems.

Excess Mg and the nervous system

Too much magnesium leads to changes in the peripheral nerves and central nervous system. This occurs due to an imbalance of electrolytes, a decrease in the concentration of Mg and K ions in the cell and its increase in the intercellular space. The result is slow reflexes, respiratory depression and even loss of consciousness. When the concentration of Mg in the blood increases to 3 mol/liter, deep anesthesia occurs. Outwardly, it looks like a dream, but it is dangerous due to the development of paralysis, lethargy and coma.

Excess Mg and muscle work

When there are too many Mg ions in the intercellular fluid, they prevent the neurotransmitter acetylcholine from being produced in normal quantities. Thus, the transmission of impulses from nerves to muscles is disrupted. The consequences are a decrease in the tone of smooth, skeletal muscles, up to the absence of their contraction, paralysis. The first sign that smooth muscles have lost tone is diarrhea, indicating excessive relaxation of the intestines. The following are:

  • muscle weakness,
  • decreased reflexes,
  • cardiac dysfunction.

Excess Mg and the heart

Magnesium relaxes the heart muscle, impairing its contractility. As a result:

  • dilation of blood vessels,
  • bradycardia (pulse rate decreases),
  • the conduction of impulses between the ventricle and atrium is disrupted,
  • decreased blood pressure,
  • heart failure.

Most often, such symptoms are observed in a vivid form in old age. In a relatively healthy adult, a disturbance in the conduction of impulses between the ventricle and atrium develops very rarely.

Symptoms of excess magnesium in the body

Symptoms of excess magnesium depend on how much of this element is in the body.

The most common health conditions caused by too high magnesium levels include:

  • circulatory arrest;
  • coma;
  • in extreme cases, death.

However, this does not mean that magnesium should be completely abandoned. Magnesium is a very important element, without which the normal functioning of the body would be impossible.

Magnesium is considered a fairly important element in the human body, as it plays a role in the structure of muscles, the nervous system, and it also affects the normalization of digestion. It is necessary that this substance enters the body in sufficient quantities to improve the absorption of calcium, as well as support the functioning of the kidneys and heart of a person at any age.

Today it is quite rare to encounter magnesium poisoning, but an overdose of magnesium still happens, for this reason it is so necessary to know what to do if symptoms of an overabundance of this substance in the body arise. It’s worth noting right away that an excess of magnesium in the body often manifests itself only in people with kidney failure, and also if a person’s metabolic processes in the body are severely impaired.

First aid for acute magnesium poisoning

  • Stop the absorption of Mg into the blood. To do this, if the drug was taken orally, you need to rinse the stomach with plenty of water.
  • Be sure to call an ambulance.
  • A calcium-containing drug must be administered intravenously, since Ca can neutralize Mg due to its opposite effect.

The hospital will constantly monitor the content of magnesium ions in the urine and blood. Doctors will also find out the reason why the body was unable to remove the excess of this element on its own. When renal failure is detected, the patient undergoes hemodialysis or peritoneal dialysis. If after this the level of Mg in the blood is still elevated, additional tests are carried out to detect cancer or dysfunction of the adrenal glands and thyroid gland.

What functions does magnesium perform?

This substance must enter the human body every day, and the full norm of this substance must be replenished per day so that the body functions without failures. Magnesium helps to improve the functioning of the nervous system, precisely when it is in abundance, the body does not experience disruptions in the transmission of nerve impulses to the brain, and the substance also has a beneficial effect on immune cells, which are obliged to protect the body from all bacteria and microbes. If there is too little of this component in the body, then the person becomes depressed and the body is more susceptible to stress. It is important to replenish insufficient amounts of magnesium, since it is responsible for the rapid absorption of calcium; only if there is enough magnesium, the patient’s teeth and bones will remain strong and healthy.

The substance is simply necessary for the muscles, as it participates in protein synthesis, helps digestion, removes toxins from the body, and also protects against the penetration of harmful substances into the organs.

Magnesium is simply necessary for the normal functioning of the heart, and if you have enough of it, you can notice a significant improvement in the normalization of blood pressure.

It helps maintain kidney function, prevents constipation, and besides all this, fights chronic fatigue.

A person needs to take a certain amount of magnesium orally per day; women must take a daily intake of 300 mg, while men must consume at least 400 mg of this substance. There are certain magnesium-containing drugs that can compensate for the deficiency of the substance in the human blood, but it is precisely because of such drugs that an excess of magnesium or an allergy to this substance in the form of tablets occurs. It is worth saying that the component is found not only in food, but also in ordinary drinking water; the higher the hardness of the water, the higher the magnesium content in it.

Daily value of magnesium for adults and children

The daily requirement of magnesium is correlated with gender and age. To ensure that the mineral is normally absorbed by the body, it is taken together with calcium in a ratio of 7:10. According to WHO, the daily intake of magnesium is:

AgeNorm, mg
Children
Up to three years81-146
Up to 8131-241
Up to 13241-591
Teenagers
Boys under 18411-761
Girls under 18361-711
Men
Up to 30401-751
Over 30421-771
Women
Up to 30311-661
Over 30321-671
During pregnancy351-711
During lactation311-671

When can doctors prescribe magnesium?

Today, many patients are prescribed a special drug called Magnesium B6, but often patients return to the doctor, complaining that they are allergic to Magnesium B6, and this is far from uncommon, since the drug is of synthetic origin. Doctors prescribe the vitamin to reduce the patient's fatigue and irritability; it is used for severe muscle pain or severe fatigue.

Excess magnesium in the body may appear due to the fact that the patient did not tell the doctor about the presence of certain diseases, for example, renal failure is an important contraindication to the use of this drug. A doctor may prescribe the use of this drug for arterial hypertension, muscle cramps that occur in athletes after training or during exercise.

Magnesium is also indicated for people who have begun to develop diabetes mellitus due to obesity or atherosclerosis; magnesium B6 is often used by pregnant women or people suffering from stress and depression.

An overdose when prescribed by a doctor is extremely rare, but still, if you take the tablets for a long time and consume a sufficient amount of magnesium with food, you may encounter unpleasant consequences of excess magnesium in the body.

List of main foods rich in magnesium

The need for admission arises after suffering stress, in the postoperative period, in alcoholics and during the formation of muscle mass in athletes.

Nature has given man many products containing magnesium. Even water contains some amount of it.

Don't forget about excess. If dietary supplements or vitamins are taken, the amount of food consumed must be changed. For example, one athlete complained that after eating 100 grams of almonds, he felt tired. There was no training that day. But he did not tell the doctor that he was taking a vitamin complex containing magnesium. Here are the characteristic signs of excess.

For what reasons can an overdose occur?

The most common cause today is hard water, it contains more salts, for this reason it negatively affects the functioning of the heart and kidneys, and also causes chronic arrhythmia. In addition, in acute and chronic renal failure, there is almost always an excess of magnesium in the body, the symptoms of which can lead to very serious consequences for the patient’s body. In addition, an overdose can occur because a person takes a large dose of a given drug; an overdose of the drug can be caused by other medications that older people use, such as constipation medications.

Mineral norm

For all its importance, magnesium is also the most vulnerable microelement in our body. Its balance is very easy to upset.

The daily requirement of an adult for magnesium is 350 - 400 mg, for children - 200 mg.

Pregnant women (450 mg), athletes and people subjecting themselves to high physical activity (600 mg) have an increased need.

Since this microelement is not produced in the body on its own, this entire dose must come from food. But, unfortunately, over the past 100 years we have begun to receive much less magnesium. Most often this happens due to poor nutrition. In the modern diet there are very few products with the maximum content of magnesium - unrefined cereals, as well as fresh fruits and vegetables. The situation is aggravated by the fast food system, which is based on the use of refined foods, excess sugar and salt, as well as products that remove magnesium from the body - for example, phosphoric acid contained in Coca-Cola and other lemonades, various preservatives and other “E” "

How does an overdose of this substance manifest itself?

It is not at all difficult to identify an excess of magnesium in the body; you just need to pay attention to some symptoms. For example, if a patient begins to experience severe muscle weakness and lethargy after using this drug, then this may be an allergy to magnesium or an overdose of this drug; these symptoms most often occur during pregnancy.

In addition, feelings of nausea may occur, vomiting and low blood pressure often occur. It is worth monitoring your heart rate, as an allergy to magnesium causes disruptions in the functioning of the heart muscle, and may also cause disturbances in respiratory function. An overdose is usually accompanied by a rare urge to urinate, and the urine becomes more concentrated.

Before taking this drug, it is best to find out from your doctor how much magnesium you need to take per day, taking into account the person’s diet, this is the only way to avoid an overdose of the drug. If you use a drug based on this substance daily without consulting a doctor, this can lead to very serious consequences, for example, the heart muscle suffers, it works weaker, which leads to failure, and the muscles of the diaphragm relax, this is fraught not only with impaired respiratory functions, but and complete respiratory depression. The weakness may be mild at first, but the more the drug enters the patient’s blood, the more obvious the signs of muscle weakness become, which can lead to complete paralysis.

An excess of this substance often develops because a person already has other diseases, for example, when the patient suffers from arthritis or psoriasis. If the overdose becomes chronic, the person experiences apathy, diarrhea, drowsiness and decreased performance.

Symptoms of hypermagnesemia, depending on Mg doses

This point will be of more interest to those who know how to read analyses. Therefore, if you are not used to understanding what is written in your medical card, move on to the next point.

An overdose of magnesium is detected when this drug in the blood plasma is more than 1.1 mol/liter. When the concentration exceeds 1.5 mol/liter, the following symptoms appear:

  • apathy,
  • drowsiness,
  • dry hair,
  • peeling, redness of the skin,
  • the skin seems hot, but there is no fever,
  • dry mouth,
  • nausea, vomiting,
  • upset stomach, dehydration,
  • decreased heart rate.

Excess Mg reaching 2.5 mol/liter causes:

  • intensification of the above symptoms,
  • serious changes in the functioning of the heart.

When the overdose reaches 5 mol/liter, the following occurs:

  • signs of Mg excess increase,
  • heart function worsens even more,
  • muscle activity appears
  • tendon reflexes change.

If the magnesium concentration exceeds 5 mol/liter the following occurs:

  • breathing disorder,
  • oxygen starvation,
  • heart failure.

With an overdose of Mg up to 7.5 Mol/liter and above, there is a high probability of cardiac arrest.

The role of magnesium for women's health

Magnesium is the #1 mineral for every woman. Because it is necessary for a normal menstrual cycle and libido (sex drive), as well as reducing the manifestations of premenstrual syndrome (irritability, tearfulness).

It is important to remember that when taking oral contraceptives, magnesium is eliminated from the body very quickly, so it is necessary to replenish it.

When a woman lacks magnesium, water is retained in the body. Therefore, she quickly loses her beauty: she looks tired, swollen, pale, and the skin loses its elasticity.

Moreover, together with many minerals and vitamins (potassium, folic acid and others), magnesium is responsible for the normal course of pregnancy, childbirth and fetal development. You can learn more about this in our article Magnesium. Importance for women during pregnancy and fetal development

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