Deadly couples. Medicines that should not be taken together


Medicines to treat diarrhea and calcium

Medicines to treat diarrhea contain loperamide, which helps the intestines form harder stool. And since calcium has much the same effect, together they can lead to constipation.

The fact that any medication should be taken strictly as prescribed by a doctor is known to everyone. But not many people know that many medications are absolutely incompatible with certain products. Meanwhile, you need to have this information - this will help maintain the level of impact of medications on the body and prevent the development of unwanted complications.

"Cefomax"

At the end of January, Roszdravnadzor ordered the withdrawal of batches of the popular antibiotic Cefomax from pharmacies. According to media reports, two series of antibiotics have proven to be very toxic - these are the CX-1703 and CX-1704 series. The rest are considered safe for now. The active ingredient of Cefomax is cefepime. This is a 4th generation antibiotic that destroys the cell walls of bacteria even at the stage of their reproduction. It is used to treat pneumonia, skin infections and diseases of the genitourinary system.

What medications should not be combined with

This section contains information about what the most common medications should absolutely not be combined with.

Antibacterial drugs

In general, drugs are considered the most “capricious”; most often, when mentioning the compatibility of antibacterial drugs with food and drinks, they mean tetracycline drugs. They are strictly not recommended to be combined with milk and dairy products - they can significantly reduce the effectiveness of the type of medication in question. It is worth giving up acidic foods and drinks - exclude carbonated sweet and sour drinks, natural juices, fruits, dry wine, dishes using vinegar and lemon juice. Be sure to avoid any alcoholic beverages.

Anticoagulants

Drugs that help should not be combined with Brussels sprouts and cauliflower, walnuts, zucchini, poultry and animals, cranberry juice, or any fatty foods. The fact is that the listed products have the exact opposite effect on the composition of the blood, due to their high potassium content. A side effect if these recommendations are not followed will be sudden bleeding.

Painkillers

Doctors do not recommend combining Pyramidon, amidopyrine and other medications with an analgesic effect with smoked products. The effect of these medications will be completely nullified, and there will be no relief from the pain syndrome.

Antidepressants

Such medications contain a monoamine oxidase inhibitor, so you cannot combine them with cheeses, sauerkraut, soy sauce, poultry, yogurt, dried fish, sour cream and raisins. All of these products contain large amounts of tyramine - this substance, in combination with a monoamine oxidase inhibitor, has a negative effect on blood pressure, sharply increasing it.

If therapy against iron deficiency anemia is carried out or these drugs are used as prophylaxis, then it is better to avoid drinking tea, any, all dairy products, flour and sweet products. These products will complicate the absorption of iron into the body and the patient will not receive the desired therapeutic effect.

Many people wash it down with milk, hoping that this will reduce the negative impact on the gastric mucosa. But when milk is combined with aspirin, the latter loses absolutely all its properties - there will be no effect from taking it.

You should not eat acidic foods and drinks while taking aspirin - this will have a stronger negative effect on the gastric mucosa and can lead to the development of gastritis and gastric ulcers.

Diuretics

You should never combine diuretics with licorice root-based medications (for example, expectorants) - this can lead to increased removal of fluid and potassium from the body, which will result in dehydration and muscle breakdown.

But keep in mind one feature of the presented medications - under their influence, potassium is removed from the body, its reserves need to be replenished. Dried apricots, beets, apples, onions, sorrel and green peas are useful for this.

Statins

These are drugs that help remove bad cholesterol from, and should not be combined with citrus fruits. Substances contained in such products block the production of liver enzymes, which can lead to increased concentrations of statins in the body. And this is fraught with muscle destruction and impaired liver functionality.

Antirheumatoid drugs

All medications from this group of medications have a very aggressive effect on the mucous membrane of the stomach and intestines. That is why, during the period of use of antirheumatoid drugs, you need to strictly adhere to a diet that involves excluding fried mushrooms from the diet and, in general, any dishes prepared by frying, raw vegetables, fruits, fish and meat broths.

Sulfonamides

These are drugs that have anti-inflammatory and antimicrobial effects and should absolutely not be combined with animal and poultry by-products, sugar and any sweets in general, any greens, or fatty foods. Sulfonamides cause suppression of kidney function - the process of urination is disrupted, so you need to drink a lot of clean water (not coffee, not tea!) while using this group of medications. Fats and sugar disrupt digestion processes, which automatically reduces the effectiveness of sulfonamides.

ACE inhibitors

These drugs are prescribed for high blood pressure and as vasodilators. If these drugs are contained in the body in large quantities, this can lead to sudden cardiac arrest. While taking the medications in question, you must definitely exclude chocolate https://site/shokolad-polza-i-vred/, dried apricots, potatoes, bananas and greens from your diet.

Bronchodilators

We are talking only about those that are made on the basis of theophylline. If they were prescribed by your doctor, then you should immediately exclude any food that is rich in carbohydrates from the menu.

Drugs that lower blood pressure

It is not recommended to include salted fish, sausage and ham in the menu while taking this group of medications. These products help reduce the effect of the drugs - it is unlikely that you will be able to lower your blood pressure.

Warfarin

Doctors prescribe this drug for prevention. In no case should you drink cranberry juice at the same time as warfarin, and in general it is advisable to avoid acidic drinks and foods - this combination increases the risk of developing gastric and intestinal bleeding significantly.

Semi-synthetic penicillins

They belong to the group of antibacterial drugs, but semisynthetic penicillins cannot be combined with orange juice, tomatoes and black coffee - these foods and drinks significantly reduce the effectiveness of the drugs in question.

Antifungal drugs

Everything is simple here - milk and all its derivatives, including cheeses and cottage cheese, are prohibited. It is these products that contribute to the growth of fungal colonies, and the effectiveness of the drugs in question comes to naught.

Antidepressants and painkillers

A dangerous combination of antidepressants and various painkillers. If a doctor prescribes treatment, he always draws the patient’s attention to the fact that drugs from these drug groups must not be taken together. But people do not always rush to see a doctor, preferring to buy inexpensive drugs at random from pharmacies, which leads to dire consequences.


The combination of these drugs can lead to the following health problems:

  • Temperature rises to critical levels.
  • Stomach bleeding.
  • Impaired mental state.
  • Increased heart rate.
  • Disturbance of the respiratory process.

A person who has taken painkillers and antidepressants at the same time experiences anxiety. He may also experience severe depression.

According to the study, it was found that antidepressants and drugs from the analgesic group can lead to severe gastrointestinal bleeding.

The influence of drinks on the effect of drugs

What do patients usually take with tablets, capsules and elixirs with syrups? Some people prefer juices, some prefer tea, and some prefer milk. But you need to understand that there are contraindications for simultaneous use of drinks with certain medications.

This drink contains a lot of tannin - a substance that forms insoluble compounds with many medications, and the result is the ineffectiveness of therapeutic measures. It is especially dangerous to take antispasmodic medications and cardiac glycosides with tea.

Alcohol

Firstly, it is strictly forbidden to use it simultaneously with taking antibacterial drugs (antibiotics). Secondly, if you use vasoconstrictor nasal drops, drinking alcohol simultaneously with this treatment can lead to a stroke. Thirdly, alcoholic drinks can disrupt heart rhythm if consumed while taking diuretics and cardiac glycosides.

In general, alcohol and any medications are absolutely incompatible! Even regular paracetamol, safe and effective at different ages, with a glass of alcohol can lead to acute renal failure.

This drink affects medications in different ways. For example, coffee should not be consumed simultaneously with sedatives and antidepressants - restlessness, feelings of anxiety and fear, and insomnia may appear. Coffee can also enhance the effect of psychoregulators, but in general it is worth knowing that if coffee is consumed simultaneously with antibacterial drugs and birth control pills, then you can expect a large accumulation of caffeine in the body, which ultimately leads to disruption of the central nervous system.

Grapefruit juice

This is generally a very harmful “thing” when conducting therapy at any level. In general, grapefruit (either in its entirety or in the form of juice) is combined with a few representatives of medications. It is this product that can increase the toxicity of antibacterial drugs and provoke a sharp decrease in blood pressure while taking antihypertensive drugs.

Please note: doctors insist that any medications should be washed down with clean water.

"Erespirus", "Erespal", "Epistat"

In February of this year, a popular Turkish-made cough medicine containing fenspiride was withdrawn from pharmacies. For the same reason, the drugs Erespal (France) and Epistat (Hungary) were withdrawn from sale. That's because experts have found that fenspiride can negatively affect heart health. In particular, in patients who were treated with Erespal, an electrocardiogram revealed disruptions in the functioning of the heart. So check your syrups for the presence of this active ingredient.

First aid and consequences

You need to understand: the victim himself most often cannot objectively assess his condition and take the necessary measures. Procedure for providing first aid:

  • rinse the stomach;
  • give an absorbent (charcoal, polysorb, smecta, polyphepan, filtrum) and a saline laxative;
  • put under a warm blanket;
  • provide air flow and unbutton clothes so that they do not impede breathing;
  • give plenty of fluids until doctors arrive;
  • do not leave unattended, do not let him fall asleep.

How to do gastric lavage correctly

When providing first aid to a victim of an overdose, it is very important to rinse the stomach in a timely and correct manner. The procedure is contraindicated in the following cases:

  • the victim is unconscious;
  • the age of the affected child is less than 2 years;
  • the person has high blood pressure or acute heart failure;
  • The victim is an epileptic. In this case, the procedure may provoke an attack.

Procedure:

  • sit on a chair. If he is unable to rise, then turn him on his side;
  • take 5 liters of warm water;
  • dissolve the sorbent in water (for 5 liters, 10 crushed tablets of activated carbon, if polysorb or enterosgel is used - 2-3 tablespoons). Also, in case of an overdose of tablets, a saline solution is used for rinsing. Salt prevents toxic substances from being absorbed into the blood and stimulates intestinal function. If time is short, you can simply use clean warm water;
  • give 500-800 ml of solution to drink. You need to drink quickly, in 2-3 approaches. Then press the root of the tongue with a spoon or fingers, thereby provoking vomiting. Use your palm to press on your stomach in the solar plexus area;
  • After vomiting, take a short break of 2-3 minutes and repeat all steps;

Important! Do not stop the procedure until the liquid becomes clear and clean.

After washing, the victim should remain in a horizontal position and apply a warm heating pad to the stomach and feet. It relieves spasms and relieves chills.

If there is time left before the ambulance arrives, it is necessary to do additional cleansing through an enema. A saline solution, as well as soda or potassium permanganate, are suitable for this.

Stages of death

Drug poisoning occurs in 4 stages. The sooner help is provided, the greater the chance of avoiding death. The rate of progression depends on individual characteristics, the type of medications taken and their quantity.

  • at the first stage, a person feels drowsiness, the pulse slows down, and salivation increases;
  • at the next stage there is loss of consciousness. The pulse is difficult to palpate, the pupils do not react to light;
  • the person falls into a comatose state. The pulse is almost invisible, breathing is shallow. Gradually, internal organs begin to fail;
  • Agony. Cardiac arrest occurs and brain activity ceases. At this stage, it is no longer possible to save the person.

It is important to understand that even with a favorable outcome, drug overdose leads to very serious consequences, most often to disability.

Opioids and acetaminophen


These medications are often prescribed to patients for a number of diseases that are accompanied by severe pain. Patients sometimes try to increase the effectiveness of one drug at the expense of another, taking them simultaneously. This ultimately leads to severe damage to liver cells, intoxication and disruption of metabolic processes. The result of such treatment may be a coma.

Anticoagulants and aspirin

In many countries, anticoagulants, which are used to reduce blood clots, are considered very serious drugs and are available only with a prescription.

But aspirin is in every home medicine cabinet and is sold without any prescription. But few people know that it also thins the blood. If you take these drugs at the same time, you risk internal and external bleeding.


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Fluconazole and statins


Statins are prescribed to lower cholesterol levels, and Fluconazole is necessary to combat fungal pathologies.
Fluconazole inhibits the processing of statins, which leads to their excessive accumulation in the body. If too many statins have accumulated in the body, there may be serious damage to muscle tissue, which will lead to disruption of vital processes in the body.

Fluconazole is usually taken for a very short course, so it is advisable to stop statins during this time.

For high blood pressure:

Last November, high blood pressure pills made from Chinese raw materials were confiscated en masse from Russian pharmacies. They had different names, but had one common ingredient - Chinese valsartan. Valsartan is correctly called a pharmaceutical substance because it is the basis for other tablets, Life explains. Laboratories in Europe, Russia and the USA make a dozen types of tablets from it. They are given new trade names: “Valz , Nortivan , Valsakor , Diovan ”, but in fact it is valsartan in different variations. European experts have found a potentially dangerous impurity of N-nitrosodimethylamine (NDMA) in Chinese raw materials. It probably got there due to an accidental change in technology or a manufacturing defect, the European agency writes. With prolonged use, the impurity can provoke cancer. In addition, NDMA hits the liver: it is extremely toxic. By that time, there were about eight million dangerous packages in Russian pharmacies.

Cough medications and antihistamines

Antiallergy and cough medications can cause death. This is explained by the fact that these drugs may contain similar components, therefore, some medications significantly enhance the effect of others, which leads to an overdose. The interaction of these medications causes a strong sedative effect. The person becomes weak and absent-minded.

The danger is that the patient, not knowing about this feature of the drugs, can drive or work with complex mechanisms. This could result in an accident or serious injury.

Before using any medicines, you must carefully read the instructions. If you have any questions, it is better to ask your doctor.

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