In case of poisoning of any type, it is important to choose the optimal drug that can quickly remove toxic substances from the body. The mild drug Phosphalugel has similar properties. When used correctly, the suspension cleanses human tissues and organs of toxins from the first use. In case of poisoning, phosphalugel also improves the function of the gastrointestinal tract, replacing a whole range of drugs.
Sachet is the only form of release of the drug.
How does phosphalugel work?
The essence of the action of phosphalugel is in its atancidal, enveloping and absorbent properties: it seems to line the walls of the stomach and intestines with a protective film, and also simultaneously neutralizes the effect of hydrochloric acid, the main active ingredient of gastric juice, and binds toxins found in the stomach. Let's take a closer look at everything this drug is capable of.
Anaticide properties are the properties to neutralize the increased acidity of the stomach, without making the reaction in it alkaline, and thus without disrupting the digestion process. Phosphalugel achieves this thanks to aluminum phosphate in a colloidal jelly form.
Adsorbent properties are the ability of a drug to absorb, bind and remove toxins and any “extra” substances: fermentation products, gases, harmful microorganisms, etc. This process is ensured thanks to the pectin and agar-agar included in phosphalugel.
The enveloping properties ensure that the drug is not absorbed by the walls of the stomach, which is especially important during intoxication: bound, blocked toxins are immediately eliminated, without entering the circulatory system from the stomach. This effect is achieved thanks to calcium and potassium salts, which form a protective thin film on the mucous membranes, reducing pain, protecting against the effects of acid and facilitating the movement of processed food in the intestines, because the drug contains sorbitol - a substance that not only gives phosphalugel a pleasant sweet taste , but also enhances peristalsis. Moreover, phosphalugel stimulates the production of its own mucus by the stomach and intestines, due to which the tissues receive protection and the ability to recover.
Clinical and pharmacological group
The product begins to act 10 minutes after administration.
The mechanism of action of the drug promotes:
- Eliminate gases.
- Destruction of viruses, pathological bacteria and toxins.
- Normalization of general condition.
- Formation of a protective mucosal membrane.
The active component of the drug prevents the process of increased production of gastric juice, which is the main cause of pathological conditions of the gastrointestinal tract. Moreover, the advantage of the product lies in its ability to maintain the acidity level not lower than the physiological norm.
A single dose has the effect of relieving the symptoms of an aggravated condition, but with a course of use in combination with other medications, a therapeutic effect is achieved.
Advantages of using the drug
Phosphalugel is very convenient to use; you should always have it in your first aid kit at home and in the car, at the dacha and at work. It is packaged in convenient single-serve sachets with two dosage options. To take the drug, simply tear the packet and, kneading it with your fingers, squeeze the contents of a pleasant orange-sweet taste into your mouth. If desired, you can also dilute the gel in water, which will not affect its effect at all. The effect comes very quickly and lasts quite a long time: literally within ten minutes pain and nausea recede, overall well-being improves, and the achieved result lasts about 3 hours.
It is very important that the drug has very few contraindications, its side effects are not severe, and it can be used by literally everyone: from newborns, for whom phosphalugel helps with colic and problems with the absorption of complementary foods, to older people, whose digestion is problematic due to age-related characteristics. The drug will not harm even pregnant women and nursing mothers if it is used correctly and the dosage is not violated.
A valuable property of phosphalugel is the possibility of its long-term use on an ongoing basis: due to the fact that it is not absorbed, does not bind and does not remove vitamins and valuable microelements (potassium, calcium, phosphorus) from the body, and also does not lead to stone formation in the kidneys and bile ducts. system.
You can use it even if you have diabetes, and don’t be afraid of its sweet taste - it is given by sorbitol, which will not harm diabetics.
The sweet taste is a huge plus when it is necessary to give the drug to small children. Combined with a very pleasant orange aroma, this makes phosphalugel a hassle-free drug that is a pleasure to take.
And lastly: there are no side effects on the nervous system. Phosphalugel does not impose restrictions on driving a car or engaging in specific activities that require high concentration of attention, since it does not dull reactions.
Indications for use
Phosphalugel - what does it help with and what can it cope with? The drug will help with such troubles as abdominal pain, a feeling of heaviness, heartburn, acid belching and an unpleasant taste in the mouth, as well as indigestion (diarrhea).
It is indicated for diseases and conditions such as:
- gastritis,
- stomach and duodenal ulcers,
- reflux effect (return of gastric juice into the esophagus),
- dyspepsia,
- liver and gallbladder diseases,
- diseases of the pancreas (pancreatitis),
- food and non-food poisoning,
- unhealthy diet with an abundance of spicy, fatty and fast food,
- binge eating,
- intestinal infections,
- alcohol intoxication,
- taking medications that negatively affect the gastrointestinal tract,
- negative consequences of radiation therapy in cancer patients,
- colic in newborns and problems with the absorption of complementary foods in young children.
The regimen and dosage of the drug always depend on the main diagnosis and the severity of accompanying symptoms, and are prescribed by the attending physician. If you follow medical recommendations, the drug can be used for a long period of time without harm to health. The drug is not used simultaneously with other medications, so as not to block their action and not bind their active substances: phosphalugel is prescribed 2-4 hours before other medications.
Reviews
Patients find positive aspects of the drug:
- Convenient stick sachet - the gel can be easily drunk from a sachet on the road if heartburn suddenly begins. You just need to knead it first.
- Pleasant taste - orange flavor adds an advantage over other sorbents. For example, Enterosgel tastes unpleasant even in the sweet version.
- The drug is beneficial in the treatment of gastritis, heartburn with vomiting.
- Suitable for pregnancy and breastfeeding.
- The medicine is available in pharmacies without a prescription.
There was a negative experience with taking the drug and an adverse reaction. The patient began to experience constipation, which resolved after discontinuation of the medication. A decrease in the effectiveness of other drugs was also noted. If you constantly need to take additional medications, you need to check with your doctor whether it is possible to combine them with taking Phosphalugel.
An antacid drug based on aluminum phosphate has a protective, sorbing and soothing effect on the stomach. The scope of application of the product covers a wide range of gastrointestinal diseases, including stomach ulcers and pancreatitis. Therapeutic use is not limited to chronic pathologies - patients have felt the help of the drug with food poisoning, heartburn, and hangover.
Safety, convenience, speed of action, efficiency – these are the characteristics of a reliable home first aid kit. Reviews from patients confirm that Phosphalugel is an excellent remedy.
Are there any contraindications and side effects?
Of course, they exist - like any drug. However, phosphalugel is different in that it has very few contraindications, and side effects can be completely avoided if you do not violate the dosage prescribed by the doctor and the rules of administration.
Among the negative effects, constipation stands out first (especially in bedridden patients and pregnant women). Side effects also include nausea and allergic reactions if you are sensitive to certain ingredients of the drug.
If it is used over a long period of time (course), a decreased calcium content in the body may be observed due to its leaching in the urine, a decrease in the amount of phosphorus and calcium in the blood, and, conversely, an increase in the concentration of aluminum. This poses a risk of kidney failure.
The fight against constipation comes down to increasing the amount of fluid you drink and taking laxatives. As for other unpleasant symptoms, they can be easily avoided by using the drug strictly according to the instructions.
So, if we talk about contraindications, then, in addition to allergies, these include:
- Alzheimer's disease, since aluminum phosphate, with long-term or excessive intake, can negatively affect the condition of brain cells;
- chronic renal failure;
- heart failure, liver cirrhosis and a tendency to constipation should be considered as limiting, but not prohibitive factors;
- In addition, phosphalugel, as a rule, is not prescribed if a person is taking tetracycline drugs, iron supplements, or.
Phosphalugel for poisoning
As we already know, phosphalgel, being an ideal sorbent, binds toxins, viruses and bacteria, gases, metabolic products in the body, as well as heavy metals, radioactive substances and allergens. All this makes it an indispensable remedy for poisoning with poisons of various origins: food, chemical, bacterial.
Take phosphalugel immediately after gastric lavage. The earlier the drug is taken, the stronger the effect. In case of poisoning, you must take the maximum daily dose (read the instructions carefully!) without diluting in water - repeated every 3 hours throughout the day, after which use the usual dosage for another two days.
Phosphalugel and alcohol
Phosphalugel removes and binds any toxins, including alcohol, which is also a poison. Alcohol has a particularly detrimental effect on the stomach, which is subject to simultaneous attack by alcohol and gastric juice, as well as spicy and salty dishes often used as snacks - naturally, the mucous membrane of the stomach and intestines suffers. However, the entire body as a whole is also poisoned, because alcohol is a poison that affects almost all organs and systems. That is why phosphalugel, with its ability to bind toxins, can eliminate severe hangover symptoms, smoothes out the consequences of “barbaric” treatment of the intestines during feasts, and can even be used as a preventive measure: if you take a sachet of the drug an hour or two before drinking is coming, its consequences will be much milder.
The regimen for using the drug for alcohol poisoning is exactly the same as for normal poisoning: after gastric lavage, it is used for 3 days, on the first day - in a double dose every 3 hours.
It is important to remember that taking alcoholic beverages and the drug at the same time is strictly prohibited.
For stomach pain
Typically, stomach pain haunts us in the presence of chronic diseases, the most common causes being gastritis and ulcers.
For gastritis, the drug is taken daily 2 hours before meals, in this case the purpose of its action is to envelop the walls of the stomach and prevent the gastric juice released with the first portions of food from corroding the mucous membranes, causing pain.
For stomach and intestinal ulcers, phosphalugel is taken 2 hours after meals to reduce acidity and prevent excess gastric juice from irritating ulcers on the mucous membrane in the intervals between meals.
Phosphalugel for diarrhea
Phosphalugel is also ideal as an emergency measure for diarrhea. To stop even severe diarrhea, take a double dose of the drug, and after 2 hours - the same amount if the diarrhea has not stopped.
Phosphalugel for heartburn
If you suffer from heartburn, to relieve the condition, it is enough to drink even half a serving - and no later than 10 minutes later relief will come. Then you can repeat it every time heartburn manifests itself again.
Phosphalugel for toxicosis in pregnant women
During pregnancy, the drug is used only as prescribed by a doctor, who usually recommends using it as a way to alleviate the period of toxicosis, as well as to eliminate heartburn - a frequent companion of pregnant women. Phosphalugel is safe for expectant mothers, because it does not remove anything unnecessary from the body - only toxins.
For toxicosis, the drug is taken 1 dose several times a day before or after meals - decide for yourself in which case relief comes faster. Carefully follow the doctor’s recommendations and instructions and do not exceed the daily dosage, because pregnant women are already prone to constipation, and the drug tends to provoke it.
And for heartburn, take the drug on an empty stomach whenever a symptom appears, keeping in mind that the interval between doses should be 3 hours.
Phosphalugel: what helps in children?
Since phosphalugel is a multifunctional drug, it is simply a godsend for children and their parents.
Phosphalugel reduces gas formation and binds released gases, making it an excellent remedy for colic - severe pain that affects many newborns, mainly under the age of 3 months.
Phosphalugel is also an excellent cure for diarrhea and bloating due to feeding errors in nursing mothers or when introducing complementary foods for which the baby’s stomach was not ready.
Older children suffer from indigestion because they often put everything in their mouths: dirty hands, unwashed fruits and various objects that are not intended for food at all. This often causes food poisoning and indigestion. And here again phosphalugel comes to the rescue - an effective and completely safe fast-acting drug, which is also important - children do not know how to endure and wait.
If a child is vomiting, phosphalugel is also prescribed, but only a pediatrician does this; self-medication is unacceptable here, because vomiting can be a dangerous symptom of diseases that are in no way related to digestive disorders.
The dosage is selected according to the doctor’s prescription depending on the age and body weight of the child.
Take care of your children and always be healthy!
Instructions for use:
Phosphalugel is an antacid drug that also has an enveloping and adsorbing effect.
The drug contains the active ingredient – aluminum phosphate. Phosphalugel neutralizes free hydrochloric acid in the stomach and also reduces the activity of pepsin. Within 10 minutes, the drug reduces acidity to a level of 3.5-5. At the same time, the antacid effect of Phosphalugel is not associated with alkalization of gastric juice, and secondary hypersecretion of HCl does not occur.
The drug is not able to be absorbed into the gastrointestinal tract. Thanks to the adsorbing effect, when using Phosphalugel, bacteria, gases, toxins, and viruses are removed from the gastrointestinal tract. Normalization of the passage of gastrointestinal contents when taking Phosphalugel is also characteristic.
Adverse reactions
Taking Phosphalugel during a hangover can cause stool retention. Constipation is especially common in older people. In this case, it is recommended to increase the amount of fluid consumed.
In addition, taking aluminum phosphate during a hangover can cause the following undesirable reactions:
- nausea, vomiting, taste perversion;
- increase or decrease in calcium levels in the body;
- renal failure;
- formation of calcifications in the kidneys;
- decreased levels of phosphorus in the bloodstream;
- increasing the concentration of aluminum in the body;
- non-inflammatory brain disease;
- insufficient mineralization of bone tissue, osteoporosis.
In older people and patients with kidney dysfunction, taking anti-hangover medication in a therapeutic dosage can cause an increase in aluminum levels in the blood. Phosphalugel in people with kidney failure can cause thirst, a drop in blood pressure, and weakened reflexes.
Indications for use of Phosphalugel
The instructions for Phosphalugel indicate the following indications for use:
- chronic gastritis (normal or increased secretion);
- acute gastritis;
- acute duodenitis;
- symptomatic ulcer of various etiologies;
- peptic ulcer of the stomach and duodenum;
- erosion of the gastrointestinal mucosa;
- hiatal hernia;
- reflux esophagitis (including in childhood);
- non-ulcer dyspepsia syndrome;
- colopathy;
- functional pathology of the large intestine;
- enterocolitis;
- proctitis;
- sigmoiditis;
- diverticulitis;
- poisoning;
- diarrhea after gastrectomy;
- acute, chronic pancreatitis;
- heartburn caused by excessive consumption of coffee, nicotine, ethanol, errors in diet, and taking medications;
- gastralgia;
- symptoms of gastrointestinal damage when taking medications, alkalis, acids;
- dyspepsia of neurotic etiology;
- prevention of absorption of radioactive elements.
Side effect
When taking this drug, a number of side effects may develop, which cause negative reviews of Phosphalugel from patients. The following side effects have been registered: vomiting, nausea, constipation, changes in taste, allergic reactions. To prevent the development of side effects, it is necessary to use Phosphalugel only as prescribed by a doctor and follow the dosage regimen.
With long-term use of Phosphalugel in high dosages, the development of hypocalcemia, hypophosphatemia, hypercalciuria, osteoporosis, osteomalacia, hyperaluminemia, nephrocalcinosis, and encephalopathy is possible.
Directions for use, dosage
Phosphalugel is intended for oral administration. The drug can be used in pure form or diluted in water.
A single dosage of Phosphalugel is 1-2 sachets (1 sachet contains 8.8 g of active ingredient). The frequency of administration is two to three times a day. In case of poisoning and burns with caustic drugs, the dosage is 3-5 sachets at a time.
For reflux esophagitis, ulcerative lesions of the gastrointestinal tract, Phosphalugel is taken before bedtime or two hours after a meal, and for pain syndrome - immediately. For diaphragmatic hernia, the drug is recommended to be taken immediately after meals and before bedtime, for enterocolitis - before meals twice a day, for colopathy - before breakfast and before bedtime.
The duration of Phosphalugel therapy is determined by the doctor based on the symptoms of the disease.
According to indications, Phosphalugel can be used in pediatrics in the following dosages: at the age of up to 6 months - 4 g or a teaspoon after each feeding (6 times); after 6 months - 8g or 2 teaspoons after each feeding (4 times).
Pregnancy
A craving for specific products and a penchant for culinary experiments accompanies pregnancy. Mixing and overusing salty, sweet, and spicy foods causes indigestion.
Toxic nausea and weakness, which are disturbing in the early stages, disappear. Acute toxicosis accompanies the entire period of pregnancy.
During food intoxication, harmful substances enter the body once, if there is no infection with E. coli. With toxicosis, hormonal changes occur, resulting in an imbalance of substances that constantly causes poor health.
Phosphalugel is safe and does not deprive the body of micronutrients. The medicine will help with poisoning in pregnant women, with mild and moderate toxicosis.
The permissible dose is 5 packets per day. In case of intoxication, take two sachets after symptoms appear. Repeat after three hours, then drink one sachet at a time. For toxicosis, take one sachet three times a day, before or after meals.
special instructions
If long-term use of Phosphalugel is necessary, it is necessary to ensure a sufficient level of phosphate intake into the body.
For unspecified diagnosis, long-term use of Phosphalugel is not recommended.
According to indications, Phosphalugel can be prescribed to patients with diabetes mellitus, since the drug does not contain sugar.
Phosphalugel can be prescribed together with cimetidine, disopyramide, ketoprofen, amoxicillin, prednisolone.
Taking Phosphalugel does not affect X-ray data.
Overdose
Increasing the dosage of Phosphalugel can lead to an excess of aluminum phosphate and other components of the composition in the body. In case of drug poisoning, constipation and severe pain in the epigastric region occur due to a single dose increase. To get rid of the signs of an overdose, it is enough to take a laxative.
Overdose can also occur with long-term treatment (more than 2 weeks). In this case, the pathological process is not limited to the manifestation of symptoms - the patient begins to develop concomitant diseases.
Diseases resulting from overdose:
- Newcastle bone disease.
- Hypophosphatemia.
- Encephalopathy.
- Kidney failure.
The listed pathologies have multiple complications, so the duration of taking the drug should be established and monitored by a doctor.
Storage conditions of the drug
Phosphalugel should be stored at room temperature out of the reach of children.
The drug "Phosphalugel" is an antacid that acts in the fight against inflammatory diseases of the gastrointestinal tract, in particular gastritis. The drug helps improve the functioning of the gastrointestinal tract and takes part in reducing the acidity of gastric juice. With long-term use of Phosphalugel, a dense protective film is formed on the mucous membrane, preventing its damage. The pattern of use of this medication corresponds to a specific ailment, so many patients are concerned with the question of how to drink “Phosphalugel” for gastritis?
Combination with other drugs
How to take Phosphalugel correctly in case of poisoning if other medications are additionally prescribed? Often, intoxication requires the use of additional drugs. These can be sorbents, probiotics, antidiarrheal tablets and antibiotics. How to combine the drug “Phosphalugel” with them?
Caution must be observed when using the following drugs: tetracycline antibiotics, cardiac glycosides and iron. Phosphalugel sachets can reduce their absorption, as a result of which the desired effect will not be achieved. Keep a break of 1-2 hours between taking these medications and the medication described in the article. The drug "Phosphalugel" can be used with other medications without additional restrictions.
Advantages
The drug "Phosphalugel" is intended to protect the gastric walls from the negative effects of incoming food and digestive juice.
The drug provides a barrier to the gastric mucosa through its ability to envelop and create a protective film. The active component is aluminum phosphate, which neutralizes hydrochloric acid in gastric juice, facilitates the passage of food and promotes the removal of toxins, waste and viruses from the body.
The main advantage of the drug is its possibility of long-term use, which is not dangerous for the disturbance of phosphorus metabolism in the body. In addition, "Phosphalugel", reducing the concentration of hydrochloric acid, does not lead to its subsequent stimulation. Due to its positive qualities, the drug is used for poisoning, gastritis, gastric ulcers, erosions on the mucous membrane of the digestive tract, heartburn, chronic pancreatitis, proctitis, inflammatory diseases, stomach pain and high acidity.
Phosphalugel is used for gastrointestinal disorders, intestinal infections, poisoning, and during therapy with medications that can cause digestive upset. This medication is prescribed for flatulence, burning sensation in the esophagus resulting from excessive consumption of caffeine, alcohol and nicotine.
Poisoning
Pathology can occur unexpectedly and for various reasons. Most often, poisoning occurs due to the consumption of low-quality or expired food. Such food can be found in small cafeterias, market squares and even in stores. To avoid poisoning, always check expiration dates and evaluate the condition of the product, and do not eat in questionable establishments.
You can be poisoned by poorly cooked meat, unwashed vegetables and fruits. Pathology may occur due to incorrect food combinations (for example, milk with pickles). There are frequent cases of drug poisoning or household poisoning. Children can be poisoned by chemical cleaning products that are within their reach.
In all the described cases, you need to consult a doctor. The doctor will tell you how to help your body cope with pathology and prescribe medications. One of the products used is Phosphalugel. In case of poisoning (this drug has different reviews), it is often recommended. What do patients say about the product? You will learn about this from our article.
How to take Phosphalugel when treating gastritis?
To treat gastritis and eliminate abdominal pain that accompanies this disease, you need to drink the medicine as follows:
- 30 minutes before meals, 20 g, which is equivalent to one sachet of medication, three times a day;
- if there are four meals a day, then you need to take the medicine at a dosage of 16 g four times a day and half an hour before each meal;
- It is more effective to take the medication with a time interval of three hours;
- It is not recommended to consume more than two sachets at one time;
- the use of medication to treat gastritis and eliminate the pain associated with this disease should continue until the patient’s condition stabilizes;
- On average, the course of treatment lasts from 4 days to two weeks.
If you know about heartburn, constant pain and disturbances in the functioning of the stomach, then you have definitely heard about this medicine. Phosphalugel is an excellent drug from the antacid group. Simply put, this is a remedy that helps reduce stomach acidity, which, in fact, causes discomfort and all unpleasant sensations. Like any medicine, Phosphalugel has its own indications for use.
What is Phosphalugel?
Phosphalugel is one of those medicines that can safely be called tasty (well, at least pleasant). The white thick liquid may not look very attractive, but it smells good of orange and has a sweetish taste. It is thanks to this that both adults and children can take Phosphalugel.
Of course, taste and smell are not the main advantages of the medicine. Phosphalugel has become famous for its rapid action - within a few minutes after taking the medicine, a person feels relief. This is achieved due to a universal composition based on 20% aluminum phosphate. The active substance quickly neutralizes hydrochloric acid, envelops the walls of the stomach with a special protective layer and promotes the removal of toxins and gases from the body.
Indications for use of Phosphalugel
Phosphalugel can be considered universal. It is prescribed for almost all disorders of the digestive system. The medicine also showed excellent results in treatment. Phosphalugel acts gently and is practically not absorbed into the blood. Once in the body, the product does not completely destroy stomach acid. The reaction continues until the acidity level returns to normal. The subsequent action of Phosphalugel is aimed solely at maintaining the achieved result.
The main indications for the use of Phosphalugel are as follows:
- Most often, the drug is prescribed for ulcers of the stomach and duodenum.
- Phosphalugel helps very well with gastritis. Moreover, both acute and chronic forms of the disease can be treated with medication.
- The product will help with diarrhea.
- It is also recommended to use Phosphalugel for hernias.
- The medicine even saves victims of alcohol poisoning.
In addition, Phosphalugel is faster than other drugs in relieving heartburn and abdominal pain caused by an unsuitable diet, consumption of low-quality products, or an overdose of nicotine or caffeine.
Methods of using Phosphalugel
You can drink Phosphalugel either by diluting the product with water (half a glass of water for one sachet of suspension will be more than enough), or in its pure form. It is best to rub the bag before use to form a homogeneous gel inside.
How long and in what quantities Phosphalugel can be taken should be prescribed by a specialist. Depending on the patient's condition and his diagnosis, the duration of treatment and dose may vary. So, for example, if a medication is prescribed to treat poisoning, then a couple of days of treatment will be enough, but to completely eliminate the symptoms of gastritis, a two-week or month course may be required. To achieve the maximum effect from treatment, you need to take Phosphalugel for as many days as indicated in the doctor’s prescription.
The standard dose is a sachet two to three times a day. If necessary, you can take two servings at once. The maximum daily dose of the drug is six sachets. It can only increase when treating serious problems - for example, severe alcohol or food poisoning.
Separately, you can remember how to take Phosphalugel for heartburn (if, of course, this problem bothers you): drink half a sachet at a time, if after ten minutes the severity does not disappear, you should finish the other half.
The drug is in the form of a white or almost white gel, sweet in taste, with the taste and smell of orange. packaged in bags. Sometimes phosphalugel is classified as a first-generation antacid (Konorev M.R.).
Active substance:
aluminum phosphate (lat.
aluminum phosphate
).
Composition of one sachet of phosphalugel
Phosphalugel is sold in two different packaging options. 10.4 g sachets and 12.38 g sachets containing the following ingredients:
| Total mass of sachet contents, g | 10,4 | 12,38 |
| Aluminum phosphate, g | 2,08 | 2,48 |
| Sorbitol 70%, g | 4,48 | 4,286 |
| Agar-agar 800, mg | 45 | 80 |
| Pectin, mg | 87 | 100 |
| Calcium sulfate dihydrate, mg | 12 | 10 |
| Potassium sorbate, mg | 40 | 53 |
| Orange flavor | 80 | 32 |
| Purified water, g | up to 16 | up to 20 |
Features of the effect of phosphalugel on the gastrointestinal tract
A special feature of phosphalugel is that aluminum phosphate micelles have a high adhesive ability, ensuring their fixation on the walls of the gastrointestinal tract and, as a result, a long duration of action, maintaining the acidity in the stomach at a level of 2.4 pH for at least two hours. The acid neutralizing ability of a daily dose of phosphalugel is 220 mEq at pH = 2.2. The increase in acidity in the stomach as aluminum phosphate dissolves occurs gradually, which avoids the phenomenon of acid rebound
. Aluminum phosphate has low toxicity, which is due to its low ability to form neutral complexes in the presence of food acids. In addition, the relative absorption coefficient of aluminum phosphate is 0.087% (aluminum hydroxide - 0.147%, sucralfate - 0.196%). On the other hand, aluminum phosphate does not interfere with the absorption of dietary phosphorus, preventing the development of phosphorus deficiency in the body, which is especially important during long-term use of phosphalugel (Belmer S.V.).
Indications for use of phosphalugel
- For all age groups - peptic ulcer of the stomach and duodenum, gastritis with normal or high acidity, reflux esophagitis
- For adults - non-ulcer dyspepsia syndrome, functional diarrhea, hiatal hernia, digestive tract disorders caused by intoxication, medications, irritants (acids, alkalis), alcohol
- For the purpose of prevention - to reduce the absorption of radioactive drugs.
Method of application of phosphalugel and dose
Adults and children over 6 years old - take 1-2 sachets of phosphalugel orally 2-3 times a day. Children under 6 months - ¼ sachet or 1 teaspoon after each of 6 feedings; over 6 months - ½ sachet or 2 teaspoons after each of 4 feedings. Phosphalugel is taken either pure or diluted in half a glass of water. Before opening, mix the contents of the bag by rubbing it between your fingers.
- For gastroesophageal reflux, reflux esophagitis, hiatal hernia - immediately after meals and at night
- For peptic ulcers of the stomach and duodenum - 1–2 hours after eating and immediately when pain occurs
- For gastritis and dyspepsia - before meals
- For functional diseases of the colon - in the morning on an empty stomach and at night
If pain occurs between doses, phosphalugel is repeated.
The use of phosphalugel in the treatment of GERD
The need for widespread inclusion of antacid drugs in treatment regimens for any clinical forms of GERD is especially emphasized in the Gstaad guidelines, on the basis of which a new multilevel European algorithm was created (see diagram below).
In this algorithm, in contrast to previous recommendations, there are 3 stages of care for patients with GERD: self-medication with over-the-counter medications (OTC), primary medical care (general practitioner) and specialized medical care (gastroenterologist). If heartburn or regurgitation occurs sporadically (once a week or less), it is possible to relieve it independently with medications usually recommended by a pharmacist at a pharmacy. At this stage, antacids are the most appropriate drugs, but if necessary, proton pump inhibitors (PPIs) and histamine H2 blockers (H2RA) can be used. With long-term use of anticidal agents based on aluminum hydroxide, which interferes with the absorption of dietary phosphates in the intestine, osteoporosis and osteomalacia may develop. This is due to the limitation of the use of aluminum-containing antacids in children and pregnant women. The exception is phosphalugel (aluminum phosphate), which does not affect phosphorus-calcium metabolism. Therefore, it can be prescribed to both pregnant women and nursing mothers, and children from birth. The use of phosphalugel may be preferable in elderly patients, who often have reduced bone density (Samsonov A.A., Odintsova A.N.). Rice. Three-level algorithm for drug treatment of GERD. BLS - over-the-counter drugs, H 2 RA - H 2 -histamine receptor blockers, PPI - proton pump inhibitors (Samsonov A.A., Odintsova A.N.).
Contraindications to the use of phosphalugel
Phosphalugel is contraindicated in cases of severe renal dysfunction or hypersensitivity to the components of the drug.
Analogs
Instead of Phosphalugel, you can take other antacids for a hangover:
- Almagel. It is produced in the form of a suspension, which contains algeldrate and magnesium hydroxide as medicinal components. Almagel taken with a hangover can cause stool retention, nausea, vomiting, taste distortion, stomach cramps, changes in mood and mental activity, allergies, increased magnesium levels in the blood, and osteomalacia. If you have a hangover, it is recommended to drink 5-10 ml of antacid three to four times a day. Children over 10 years old with alcohol intoxication are prescribed to drink Almagel at half the dose for adults. From 15 years of age, the dosage of the medicine corresponds to the dose for adults.
- Gastal. The drug is produced in lozenges. They can be taken for heartburn and other dyspeptic disorders that occur with a hangover.
Despite the compatibility of Phosphalugel with alcohol and the over-the-counter availability of the medication, it is not recommended to take it for a hangover without consulting a doctor, since the medicine has contraindications and can cause unwanted reactions.
